https://zd6474inhibitor.com/me....chanism-regarding-gu
Furthermore, Zscan4 exhaustion causes elevated DNA damage in 2C mouse embryos in a transcription-dependent manner. Together, our outcomes identify Zscan4 as a DNA sequence-dependent microsatellite binding element and suggest a developmentally controlled mechanism, which protects fragile genomic areas from DNA harm at a time of embryogenesis involving high transcriptional burden and genomic anxiety. Copyright © 2020 The Authors, some l
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