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How Does Medication For ADHD Work? Many kids and adults discover that ADHD medication helps improve their ability to concentrate, control impulses and become organized. Your doctor will collaborate with you and your child to determine the most effective medicine for them. Stimulants are the primary treatment for ADHD. They increase levels of dopamine and norepinephrine. Stimulants Stimulant medications for ADHD work by increasing levels of certain brain chemicals (called neurotransmitters). This hel