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© 2020 The American Geriatrics Society.BACKGROUND While most known causes of infertility relate to the health of the woman and/or her partner, questions have been raised regarding the possible contributions of transgenerational or epigenetic factors. OBJECTIVE The goal of this hypothesis-generating work was to examine whether Generation 1's (G1's) age at the delivery of G2 (Generation 2) was associated with G2's fertility in later life. METHODS We conducted a retrospective cohort study of women (G2s) recruited online in 2016. A question