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This review will explain the part of CD47 in myeloid malignancies and pre-clinical information encouraging CD47 targeting. In addition, preliminary medical data of CD47 targeting in AML/MDS are reviewed, and such as the first-in-class anti-CD47 antibody magrolimab. Copyright © 2020 Chao, Takimoto, Feng, McKenna, Gip, Liu, Volkmer, Weissman and Majeti.Emerging information on the gene appearance and mutational popular features of canine lymphoma and