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In the present research we centered on the impact of TFAM in the relation involving the oxidative damage caused with the addition of glucocorticoid to a hypoxic environment and osteocytic cell necrosis. Using cultured osteocytes MLO-Y4 in a 1% hypoxic environment (hypoxia) to which 1µM dexamethasone (Dex) ended up being included (De+)/hypoxia(+)), an immunocytochemical study ended up being carried out making use of 8-hydroxy-2'-deoxyguanosine (8-OHdG), an index of
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