https://www.selleckchem.com/pr....oducts/dinaciclib-sc
Novel therapeutic strategies are urgently required for the clinical management of chemoresistant ovarian carcinoma, which is the most lethal of the gynecological malignancies. MicroRNAs (miRNAs) hold promise because they play a critical role in determining the cell phenotype by regulating several hundreds of targets, which could constitute vulnerabilities of cancer cells. A combination of gain of function miRNA screening and real-time continuous cell monitoring allows the identification of miRNAs with robust cytotoxic effec