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In comparison, detrimental effects of Treg tend to be due to suppression of antiviral resistance, allowing for virus determination and latency. Opposing condition results after Treg manipulation in various designs may be related to variations in method and timing of intervention, infection route, hereditary history, plus the host's age. In addition, mouse types of virus-induced demyelination revealed that Treg are able to reduce autoimmunity and immune-mediated CNS damage in a dise
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