https://www.selleckchem.com/products/Y-27632.html
In Tg glands, FAE increased the luminal progenitor cell population at 5 weeks of age but did not alter MEC composition at 10 weeks of age. Tertiary mammosphere-forming efficiency was greater in the WT glands of FAE animals at 10 weeks of age. Tumor latency was decreased in the FAE group. Flow cytometry analysis indicated that FAE females developed tumors with an increased basal cell population. CONCLUSIONS These data indicate that FAE can shift MEC subpopulations, increasing the proportion of cells that are potentially vulnerable to tra