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05), and in the EMD-38-group compared to the S-38-group (p.05). The levels of C-III and OPN immunoreactivity were significantly higher in the ABS-10-group compared to the S-10-group (p.017). The results of this study suggested that ABS can promote early periodontal regeneration, although its efficacy seems to decrease over time. The results of this study suggested that ABS can promote early periodontal regeneration, although its efficacy seems to decrease over time. Trough-adjusted tacrolimus is commonly prescribed following intes