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g., H6 and thus the escaping behavior of copper ions and the catalytic activity. This work opens a new route for nano-hybrid-enzyme design and enzyme activity regulation with chiral carbon materials as functional domains via remote target interaction.From a green chemistry perspective, sustainable irradiation as the power source and water as the solvent have certainly grabbed the attention of chemists in recent times because their use helps reduce the hazardous ecological footprints of organic synthesis. In the present work, we have e