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No effect was found for changes in BMI over time. Individuals from a non-clinical population showing diet-related compensatory behavior more frequently seem to have an improved diet quality and an increase in physical activity over time. Therefore, when applied in healthy doses, diet-related compensatory behavior may contribute to the maintenance of a balanced and healthy body weight, but it is not a successful strategy for weight loss over time.We have previously shown that sphingosine kinase 2 (SPK2) interacts with Bcl-2 via its BH3 do