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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression Untreated ADHD can result in chronic underachievement and depression. This is particularly true when they fail to meet their personal and professional goals. It aren't always easy to determine when there are commonalities in symptoms between ADHD and depression. Identifying the symptoms is a good first step towards seeking treatment. 1. Feelings of unworthiness Many people with untreated ADHD or depression that co-occurs st