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ng could help to target psychotherapeutic treatments and improve screening. Key points Patients with high psychological pain do not differ on the Trail Making Test, the Stroop Test or the Sematic Verbal Fluency Measure to patients with low psychological pain High psychological pain is associated with a deficit in phonemic verbal fluency in depressed men Future research should aim to clarify gender differences in psychological pain in participants with and without major depressive disorder, as well as explore the complex relationship be