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29 compared to HCV 0.2 (p less then 0.001) and HIV 0.21 (p = 0.037) group. The adjusted analysis where we consider age as possible confounder revealed that only IL-2 significantly differs for all groups compared with control group control vs HCV (p = 0.001); control vs HBV (p = 0.024); control vs HIV (p = 0.004). CONCLUSIONS Evidence for significant differences when comparing oral fluid cytokines of individuals with HCV, HBV and HIV with non-viral individuals was more obvious for IL-2. IL-2 levels were significantly higher in all 3 grou