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Relevant application of hydrogel-based spots allowed the acceleration of injury healing additionally the total healing, for composite hydrogel enriched with carotenoids.Hydrophobin-1 (HFB-1) found on the area of fungal spores, plays a role in having less antigen recognition because of the number immune protection system. The present study aimed to guage the potential application of HFB-1 for the distribution of doxorubicin (Dox) into different cell outlines. Coating the outer lining of niosomes (Nio) with HFB-