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Interestingly, pharmacological interventions, which proved to be successful in different models of ChAc, were ineffective in treating the observed axonal phenotypes. Our data suggests that treatment of this multifaceted disease might be cell type and/or neuronal subtype specific, and thus necessitates precision medicine in this ultra-rare disease.Many practical aspects of processing fresh concrete depend on its rheology, such as the pumping of the material. It is known that a lubricating layer is formed in the process, which significantly reduces the pumpin