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ADHD Medications and Treatments Stimulants are the main medications used to treat ADHD. They increase neurotransmitters and help control impulses and improve concentration. Adderall and dextroamphetamine are just two examples, as are methylphenidate, lisdexamfetamine and Ritalin as well as their brand names. If stimulants don't work or cause too many side effects, doctors may prescribe antidepressants such as Wellbutrin. These drugs target norepinephrine and dopamine levels in the b