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0512) and PFS in the T4 subgroup ( = 0.0417), while contrary to the T2-3 subgroup. CT-quantified body compositions have a significant influence on CRC patients successively underwent curative resection and regularly standard chemotherapy with the endpoints of 1-year, 3-year, and 5-year both OS and PFS. Patients with high-SM showed a strikingly poor prognosis in OS and PFS in the T4 subgroup; however, the prognosis role of body composition was opposite in T2-3 patients. CT-quantified body compositions have a significant influence on CRC