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We discovered that circIFI30 was significantly up-regulated in TNBC cells and cells using quantitative real-time PCR and in situ hybridization. High circIFI30 expression was positively correlated with clinical TNM stage, pathological grade and poor prognosis of TNBC clients. Functionally, a series of in vivo plus in vitro experiments revealed that knockdown of circIFI30 could markedly prevent TNBC mobile proliferation, migration, intrusion and cellular cycle progression, induce apop