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We subsequently evaluated miR-130b expression in our clinical OPSCC cases. Values of miR-130b 5.372 (low expression), determined from receiver operating characteristic curve analyses, were associated with significantly longer progression-free survival and overall survival ( = .006, = .04, respectively). Our results suggest that miR-130b has potential as a biomarker for the radiosensitivity of HPV-negative OPSCC. Our results suggest that miR-130b has potential as a biomarker for the radiosensitivity of HPV-negative OPSCC.Metabolic