https://www.selleckchem.com/products/ldk378.html
Obesity is a major risk factor for diabetes and cardiovascular diseases such as hypertension, heart failure, and stroke. #link# Impaired endothelial function occurs in the earliest stages of obesity and underlies vascular alterations that give rise to cardiovascular disease. However, the mechanisms that link weight gain to endothelial dysfunction are ill-defined. Increasing evidence suggests that endothelial cells are not a population of uniform cells but are highly heterogeneous and are organized as a communicating multicellular network