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The thermogravimetric evaluation reveals that the 0.33 mmol DOTA groups have now been grafted per gram of silica. But, during the Lu ion complexation, a 10 times lower Lu adsorption ability of 0.03 mmol g-1 could possibly be achieved beneath the examined response problems. The outcomes suggest that the grafting of DOTA on solid strikes the Lu coordination as well as affects the kinetics of Lu-DOTA complexation. The poor control resulted in high 177mLu leakage, while the unreacted DOTA groups