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Significantly greater concentrations of n-3 PUFAs (total, DPA, and DHA) and n-6 PUFAs (total, ARA, and 224) were seen in participants with improved (versus progressed) status of MetS (all Ps trend ≤0.003). SUMMARY this research shows that higher erythrocyte VLC n-3 and n-6 PUFAs, but lower 18-carbon PUFAs (ALA and GLA), tend to be involving lower dangers of MetS components (HTG, hypertension, and reduced HDL cholesterol) and thereby lower MetS incidence in Chinese adults