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In two cases with diagnostic tissue on CT-guided biopsy, an open biopsy was still recommended based on the clinical scenario; in both cases the open biopsy results matched those of the CT-guided biopsy. Among 18 patients who required surgery, there was a 100% correlation between percutaneous needle biopsy and final pathological diagnosis. There were no biopsy-induced complications or extra-spinal seeding of tumor. CONCLUSIONS CT-guided biopsy is a safe and effective technique. It represents a critical compone