https://www.selleckchem.com/pr....oducts/fti-277-hcl.h
OBJECTIVE Advanced chronic kidney disease (CKD) carries an increased risk for progression to end-stage renal disease (ESRD). We aimed to determine the rate of progression and the factors that drive the decline of renal function in lupus nephritis (LN). METHODS Patients with advanced LN-related CKD were identified from our longterm longitudinal cohort. Advanced CKD was defined as stage 3b (eGFR=30-44ml/min/1.73m2) and stage 4 (eGFR=15-29ml/min/1.73m2). All individuals were followed until progression to ESRD or the last visit and were