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How Does Medication For ADHD Work? Stimulants can enhance your attention and impulse control by increasing the levels dopamine and norepinephrine within your brain. They are available in immediate-release (short acting) and extended release tablets, which can be taken once daily in the morning. Nonstimulant medicines can enhance concentration and impulse control, but they are more difficult to use. Atomoxetine, Viloxazine and guanfacine are antidepressants that increase norepinephrine levels. Stimulants