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The studies of an identical role of IL-31 in CTCLs are less homogenous. Due to contradictory reports concerning IL-31 and CTCL we've analysed offered literature in summary its role, concentrating on CTCL and AD.Dermal paraneoplastic syndromes tend to be non-malignant conditions, triggered ultimately by the upsurge in growth factors or as immunological responses, which result in a number of inflammatory, hyperkeratotic or proliferative skin responses. They could occur as