https://www.selleckchem.com/pr....oducts/tbk1-IKKe-in-
The activation of hepatic stellate cells (HSCs) is a key event in schistosome-induced liver fibrosis. Previous studies have shown that soluble egg antigens and the recombinant P40 protein from eggs inhibit HSC activation. In the present study, we observed the direct effect of the recombinant (r)SjE16 protein on HSCs. The sequence of SjE16 was analyzed by bioinformatics. Then western blotting, quantitative PCR, and MTT assays were performed to observe the effects of rSjE16 on HSCs. The SjE16 protein has no signal peptide