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and T2* changes of knee cartilage after marathon were evaluated by MRI and automatic segmentation software. This study was the first to use cartilage automatic segmentation software to evaluate the effects of marathon on the morphology and biochemical components of articular cartilage, and to predict the most vulnerable articular cartilage subregions, for the convenience of future exercise adjustment and the avoidance of sports cartilage injury. We investigated the efficacy and exposure to radiation in 320-detector row computed tomogra