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en used appropriately in the context of a balanced diet and physical activity. Still, it is necessary to be cautious with the consumption of certain sweeteners since the effects of LNCS on the intestinal microbiota or its effect on premature deliveries, among others, have not been fully elucidated. Conclusions it is essential to carry out further studies in order to clarify/establish the safety and value of sweeteners as food ingredients/additives in the medium/long term, in a model of increasing consumption as a consequence of the refo