https://www.selleckchem.com/pr....oducts/h-1152-dihydr
BACKGROUND Excess dietary sugar is associated with deleterious metabolic effects, liver injury, and coenzyme-Q10 (CoQ1 deficiency. This study investigates the ability of CoQ10 to protect against fructose-induced hepatic damage. METHODS Rats were fed tap water or 30% fructose for 12 weeks with or without CoQ10 (10 mg/kg, po). An additional group of rats were allowed to feed on either water or 30% fructose for 12 weeks, followed by four weeks of treatment with either the vehicle or CoQ10. RESULTS Fructose-fed rats showed