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The best mass resolution obtained in this study is m/Δm = ∼20. Preparative mass spectrometry using RWMA provides the advantages of simplicity, compactness, and low fabrication cost, which are particularly promising for the development of miniaturized instrumentation. The results presented in this work can be readily adapted to preparative separation of a variety of charged species of interest to the broad scientific community.Preclinical and clinical data suggest that acetyl-CoA carboxylase (ACC) inhibitors have the potential to rebalance disordered