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1 g/L, p = 0.006) and Ishak fibrosis scores (3.4 vs. 4.1, p = 0.01 at diagnosis, and they appeared to achieve biochemical remission more rapidly (1 vs. 3 months, p less then 0.001). Of note, patients with histological remission had higher frequency of fibrosis regression than those with persisting histological activity (87.5% vs. 60%, p = 0.004). In conclusion, lower serum IgG levels, less fibrosis in liver histology at diagnosis, and rapid response to immunosuppressive therapy are reliable predictors of biochemical and histological re