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peripartum period may be crucial in PPCM pathophysiology. Registration URL https//www.clinicaltrials.gov; Unique identifier NCT00998556. ERBB4 is essential to protect the maternal heart from peripartum stress. Downregulation of ERBB4 in cardiomyocytes induced by multiple miRNAs in the peripartum period may be crucial in PPCM pathophysiology. Registration URL https//www.clinicaltrials.gov; Unique identifier NCT00998556.Active targeting is a prospective strategy for controlled drug delivery to malignant tumor tissues. One of the approac