https://www.selleckchem.com/pr....oducts/pf-03084014-p
Orthodontic tooth movement (OTM) has been widely observed worldwide. The OTM process is involved in several biological activities and can result in temporary hypoxia. The dynamic changes of autophagy and apoptosis during OTM have not, to the best of our knowledge, been previously reported. In the present study, an OTM animal model was established. Periodontal ligament cells (PDLCs) and osteoclasts were investigated using HE and tartrate-resistant acid phosphatase staining. The changes in the expression levels of cert