https://www.selleckchem.com/pr....oducts/dabrafenib-gs
CePO /CS/GO scaffold activates the caspase-3 proteasein local tumor cells, thereby lysing the DNA between nucleosomes and causing apoptosis. On the one hand, the as-released Ce ions promote M2 polarization of macrophages, which secretes vascular endothelial growth factor (VEGF) and Arginase-1 (Arg-1), which promotes angiogenesis. On the other hand, the as-released Ce ions also activated the BMP-2/Smad signaling pathway which facilitated bone tissue regeneration. The multifunctional CePO /CS/GO scaffolds may become a promis
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