https://www.selleckchem.com/pr....oducts/crenolanib-cp
In our recent study, we demonstrated that certain limonoids isolated from citrus seeds induced apoptosis in human pancreatic (Panc-28) cells. In this study, limonin, nomilin and limonexic acid (LNA) were investigated for understanding the possible mode of cytotoxicity in cultured pancreatic cancer (Panc-28) cells. All three limonoids inhibited Panc-28 cell proliferation, with IC50 values less than 50 μM after 72 h of incubation. The induction of apoptosis was confirmed through the cleavage of caspase-3, decreased mitochondr
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