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The CK-18 M30, IL-28B, liver purpose and bloodstream lipid had been detected. The pathology of liver cells was seen by HE staining. The ROC curves of liver pathological results, IL-28B, and CK-18 M30 were plotted therefore the sensitivity/specificity of each and every index had been computed . RESULTS The liver structure pathology at the end of the twelfth week satisfied NASH diagnostic criteria. The liver pathological results of NASH model were greater than those associated with