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The purpose of this organized analysis is always to gather and summarize the most up-to-date data regarding exosomes to determine their possible effect in bone tissue and periodontal regeneration. Digital databases (Pubmed, Web of Science) were searched as much as February 2020. Studies assessing the impact of exosomes management in experimental bone and periodontal flaws have-been identified in accordance with PRISMA tips. Among the list of 183 identif