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Molecular analysis of cyst fluid was carried out on 108 PCLs that had concurrent CEA and/or cytological analysis. A 48-gene NGS assay ended up being utilized, including genes commonly mutated in mucinous PCLs such as for example GNAS, KRAS, CDKN2A, and TP53. KRAS and/or GNAS mutations had been present in 59 of 68 (86.8%) cases with multimodality diagnosis of a mucinous PCL. Among 31 clients where medical histo