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Serum levels of estradiol, FSH, and LH were calculated making use of the immunoassay technique. All analytical evaluation was carried out utilizing SPSS software. From the 255 individuals, diabetes duration-matched, 35 premenopausal, and 57 postmenopausal women had been selected for evaluation. The amount of estradiol, LH, and FSH had been discovered becoming comparable in participants with and without DR among pre- and post-menopausal females with diabetes