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Interestingly, metastasis displayed a dramatically increased infiltration by CD1a-positive dendritic cells in addition to increased CD3+ and CD8+ cytotoxic T cells. Increased infiltration associated with the metastatic tumor by CD1a+ antigen presenting cells warrants further investigation to evaluate its potential predictive value. Lung neuroendocrine carcinoma (NEC) is described as intense medical behavior and not enough therapy advances. We evaluate the prognostic pl