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Medication For ADHD - What Are the Side Effects? Many people who suffer from ADHD experience a reduction in symptoms when taking medication. Each person's reaction to drugs is different, and side effects can be a problem. Methylphenidate belongs to a class of medications called stimulants. It works by raising levels of a substance in the brain that assists in controlling the behavior and attention. Stimulant medications Stimulant drugs improve attention and concentrati