https://www.selleckchem.com/pr....oducts/1-naphthyl-pp
Our model predicted plasma concentrations in infants in agreement with the observed data (average fold error of 0.9. The PBPK model-predicted clearance in a virtual infant population was successfully able to capture the post hoc estimated clearance of meropenem in this population, estimated by a previously published model. For 90% of virtual infants, a 4-mg/L target plasma concentration was achieved for 50% of the dosing interval following product label-recommended dosing. Our PBPK model supports the meropene
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