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ation. This large US retrospective database study demonstrated the substantial HCRU and cost burden of THA dislocation. The present study was conducted to formulate and investigate liposomes for the dual drug delivery based on anti-tubercular drug(s) combination i.e. Isoniazid (INH) and Rifampicin (RIF). Mannosylated and non mannosylated liposomes were prepared by lipid thin film hydration method, using DSPC Chol at a molar ratio 64 while in case of mannosylated liposomes DSPC Chol Man-C4-Chol at a molar ratio 6.03.50.5 were used and exte