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FMT exerted additionally a significant restoring effect in TJ by increasing occludin (56 ± 15%) and claudin-1 (84 ± 7%) expression. The useful effects of these treatments on instinct barrier purpose generated significant decrease in systemic endotoxemia (EU/ml, mean ± SD Group I 0,93 ± 0,36, Group II 2,14 ± 1,74, Group III 1,48 ± 0,53, Group IV 1,61 ± 0,58,), while FMT additionally decreased IL-6 and IL-10 amounts. Conclusion Fecal microbiota transplantation and stress dose hydrocortisone adm