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The patients with zinc deficiency had a higher risk of OHE than those without zinc deficiency (p=0.03). Zinc deficiency was also associated with poor survival (p=0.004). Multivariate analyses showed that zinc predicts the development of OHE (subdistribution hazard ratio [HR], 0.95; 95% confidence interval [CI], 0.92-0.99; p=0.008) and mortality (HR, 0.96; 95% CI, 0.93-0.99; p=0.02), independently of liver function reserves. Zinc deficiency is likely to be a predictor of both OHE development and mortality in LC patients with MHE. Zinc def
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