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Topics aged two decades through the Korean National medical health insurance Service-National Sample Cohort were enrolled from 2002 to 2013. In study We, a total of 60,178 despondent patients were matched 14 with 242,872 control I subjects. In research II, a complete of 4,328 SSNHL patients had been 14 coordinated with 17,312 control II subjects. These people were coordinated for age, intercourse , earnings, and area of residence. The Charlson comorbidity list (CCI) was adjusted. Subgroup evaluation had been perfor