https://www.selleckchem.com/pr....oducts/milademetan.h
We summarize key mechanisms of how DUBs control embryonic and postnatal differentiation processes, highlight developmental disorders that are caused by mutations in particular DUB members, and describe our current understanding of how these mutations disrupt development. Finally, we discuss how emerging tools from human disease genetics will enable the identification and study of novel congenital disease-causing DUBs.Ferroptosis is an iron-dependent form of regulated necrosis associated with lipid peroxidation. Despite its key role
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