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The data were collected by means of the OFER and ENSS questionnaires, which had been translated into Indonesian and tested for their validity and reliability. A statistical test showed that there was a significant difference in the effect of the shift-work schemes on nurses' work-related fatigue (p=0.012), but there was no meaningful difference in the effect of the schemes on their work-related stress (p=0.267). It was revealed that there was a difference in the influence of shift work on work-related fatigue, but there was no significan